Extrusion

Extrusion is at the core of AdvantaPure. Our high-purity tubing and hose products are manufactured in ISO-certified cleanrooms using advanced extrusion technologies, ensuring consistent quality, compliance, and performance for critical pharma and biopharma applications.

With facilities in the United States and the Netherlands, we provide business continuity and reliable supply to customers worldwide. Our processes are supported by rigorous quality systems, full lot traceability, and a dedicated team of experts who ensure precision in every product we deliver.

We’re also committed to sustainability, with operations powered in part by solar energy and reusable resources. At AdvantaPure, extrusion is more than manufacturing—it’s expertise, reliability, and innovation working together to support our customers’ success.

Overmolding

Overmolding at AdvantaPure

Overmolding is a key capability within AdvantaPure’s manufacturing operations. Our single-use molded manifolds and assemblies are produced using precision injection molding and overmolding techniques to create seamless, leak-free connections that reduce the need for barbs, fittings, and clamps.

Using overmolding eliminates potential leak points and instead creates a seamless, continuous flow path—ensuring the most efficient fluid transfer when compared to mechanical assemblies.

Components such as wye, tee, cross, reducer, and Tri-Clamp styles are manufactured in ISO-certified cleanrooms, using high-purity materials including AdvantaSil platinum-cured silicone and AdvantaFlex TPE. This approach provides a consistent single-material contact surface, improving cleanliness, reliability, and process integrity in biopharmaceutical applications.

Supported by rigorous quality systems, full lot traceability, and technical expertise, AdvantaPure’s overmolding processes ensure consistent performance and compliance with the industry’s demanding standards.

Assemblies

Complex fluid transfer often requires more than tubing or molded parts alone. AdvantaPure assemblies bring these elements together into complete, ready-to-use systems that are engineered to reduce manual connections, save time, and improve process reliability. By integrating tubing, connectors, filters, and other components in a controlled cleanroom environment, we deliver assemblies that are consistent, sterile, and optimized for biopharmaceutical applications.

Our technical experts work closely with customers from concept to production, offering both standardized options and fully customized designs. Leveraging our extensive component library—or developing new solutions when needed—we tailor each assembly to maximize flexibility, accelerate implementation, and meet the unique requirements of your process.

Every assembly undergoes strict quality control and is fully documented for lot traceability. The result is a dependable solution that supports efficiency and compliance while reducing the burden of in-house assembly.